I have a question about calf botox.

My calves are the type where my muscles are well-developed and my thighs and ankles are thin, so my calves look relatively thicker. These days, body botox is becoming more popular and cheaper, so I'm interested in calf botox. However, I've heard that calves can develop tolerance to botox because they require a large dose. If I stick to the right schedule, will it be okay? Also, I'm wondering if it's okay to get botox for facial wrinkles at the same time I get calf botox, or if it's better to wait a certain amount of time before getting botox for wrinkles?