[Vitaran] Rejuran vs. Vitaran: The Difference? We compare effectiveness, pain, and even the number of treatments.

https://blog.naver.com/maypure_gangnam/224342713950

hello.

Chief Director of Maypure Gangnam Branch, Choi Hee-won no see.

When we look into skin boosters because we are concerned about skin texture or fine lines

Rejuran? It comes out a lot. But there is a product that always comes out together with Rejuran.

Vitaran is effective and popular at Maypure Gangnam Branch as well.

then What is the difference between "Rejuran" and "Vitaran" ,

I am wondering which product I should choose.

Both products are extracted and purified from the DNA of salmonid fish

PN (Polynucleotide) component It uses

The PN injected into the skin creates a physical tissue repair environment for a certain period

It is also similar in that it is a medical device designed to form.

First, to start with the conclusion

However, just because they belong to the same PN series does not mean the two products are completely identical,

It is difficult to say that one product is unconditionally better than the other.

The choice may vary depending on skin thickness, treatment area, pain sensitivity, and the desired direction of improvement.

today Differences between Rejuran and Vitaran, effects, pain, number of treatments, and selection criteria second

I will compare them objectively.

What is the difference between Rejuran and Vitaran?

The key ingredients of Rejuran and Vitaran are all PN (Polynucleotide) no see.

The difference appears in the following areas rather than in the component called PN itself.

Manufacturer and raw material refining and manufacturing technology

Viscosity and physical properties by product

Product composition including eye area, face, etc.

Formulation design for pain control

Clinical data and scope of domestic approval

Depth and volume used during the actual procedure

Therefore, rather than choosing based solely on the brand name,

It is recommended to check the type of product actually used and the treatment area together.

Similarities between Rejuran and Vitaran

Rejuran and Vitaran are both

We use PN components made by purifying DNA derived from salmonid fish.

PN is a polymeric material composed of multiple nucleotides linked together.

When injected into the skin, rather than significantly filling specific areas like a filler,

It stays within the skin tissue for a certain period of time

It gradually decomposes after forming a physical tissue repair environment.

Both products are generally considered for the following skin concerns.

but Improves pores, redness, acne scars, and internal dryness silver

The perceived results may vary depending on individual skin condition and the treatment method.

The purpose of the product's official approval and what is expected in actual clinical practice

Additional changes must be explained separately.

In actual practice, for the purpose of improving fine pores, fine lines, mild redness, and internal dryness

You are choosing Rejuran and Vitaran.

What kind of skin booster is Rejuran?

Rejuran is a PN-based medical device for tissue repair manufactured by PharmaResearch.

Among domestic PN skin boosters, it has been used for a relatively long time, and

Rejuran, Rejuran Eye, Rejuran S, Rejuran HB plus, etc.

There is a wide variety of product lines to choose from depending on the purpose of the procedure.

Generally, they are classified as follows.

Rejuran: Facial skin texture and fine lines care

Rejuran Eye: Skin as thin as the eye area

Rejuran S : Locally sunken or hollowed areas

Rejuran HB plus : Products containing hyaluronic acid and lidocaine in PN

In addition to PN, Rejuran HB plus is a moisturizing ingredient

It contains hyaluronic acid and lidocaine, a local anesthetic,

You can choose this option when considering both moisturizing effects and procedure pain.

The advantage of Rejuran is that it has a diverse product line and has accumulated extensive experience in actual clinical use.

However, general PN products A stinging or aching pain may occur during injection,

Immediately after the procedure, an embossing effect may occur at the injection site.

What kind of skin booster is Vitaran?

HP Vitaran is a PN-based tissue repair medical device manufactured by BR Pharm.

The main ingredient of Vitaran is also Sodium polynucleotide is,

In Korea Approved for the purpose of temporarily improving fine lines at the corners of the eyes in adults. I received it.

Vitaran also has products with different physical properties, such as the standard type, Vitaran Eye, and Vitaran S.

In particular, Vitaran Eye adjusts the pH and ionic environment of the PN formulation

It was designed to reduce pain and embossing during the injection process.

Even in a study that directly compared Vitaran Eye and Rejuran Eye

such Possibility of pain reduction due to formulation differences This has been confirmed.

The clinical trial for the approval of Vitaran was conducted on 250 people,

In the evaluation 12 weeks after the final procedure, following a total of 4 procedures performed at 2-week intervals,

The percentage of patients whose fine wrinkles at the outer corners of the eyes improved by one grade or more was 93.2% for the Vitaran group and 92.8% for the control group.

This is the effect of Vitaran compared to other PN skin boosters (Rejuran, Lizne, etc.)

It also means that it is similar to or slightly higher than existing products.

Rejuran vs. Vitaran at a Glance

Is Vitaran less painful than Rejuran?

In a study that directly compared Vitaran I and Rejuran I

Vita's child had a lower pain score. .

To 15 participants, a Vitaran eye in one eye,

On the opposite side, in a randomized split-face study in which Rejuran Eye was injected,

The average pain score was as follows.

Vitaran Kid: 3.39 points

Rejuran Eye: 5.01 points

Embossing after the procedure was also observed in 13.3% of Vitaran Eye and 56.7% of Rejuran Eye.

Both products improved wrinkles at the corners of the eyes, and

No statistically significant difference was confirmed in the degree of wrinkle improvement.

Among those who received treatment comparing the two products at Maypure Clinic Gangnam Branch

There were quite a few cases where people felt relatively comfortable with Vitaran.

However, this is based on our clinic's clinical observations, and pain varies from person to person.

In addition, direct comparative studies Vitaran I and Rejuran I Since it is a study of 15 people comparing,

The results cannot be applied equally to all Vitaran products and all Rejuran products.

Therefore, it is accurate to understand it as follows.

Which is more effective, Rejuran or Vitaran?

Based solely on the currently available direct comparison data

It is difficult to conclude that one product is superior in every aspect of skin improvement effects.

In a study comparing Vitaran I and Rejuran I

Both products improved wrinkles at the corners of the eyes, and

When evaluated up to 12 weeks after the final procedure

There was no significant difference in the degree of wrinkle improvement between the two products.

In addition to the product name, the following factors influence the actual effect.

Whether it's the eye area or the whole face

Whether the skin is thin or thick

Degree of fine lines and dryness

Dose injected into one site

Intradermal injection depth and interval

The practitioner's injection method

in other words, The difference between Rejuran and Vitaran is not simply the superiority or inferiority of the ingredients.

Differences in product physical properties and treatment plans It is best to understand it as such.

Is Rejuran better for the whole face, and Vitaran better for the eye area?

It is not necessarily distinguished that way.

Both Rejuran and Vitaran have eye area and general-use products within the brand.

For thin areas like the eye area, select a product with suitable viscosity and spreadability, and

For the entire face, you must determine the product and dosage suitable for skin thickness and wrinkle condition.

The purpose of Vitaran's official domestic approval is the temporary improvement of fine lines at the corners of the eyes.

Therefore, when performing the procedure on the face or neck

The purpose of approval, the physical properties of the product, the characteristics of the treatment site, and the judgment of the medical staff must be considered together.

Rather than simply dividing it into “Rejuran for the whole face, Vitaran for the eye area”

It is important to verify the actual product type and treatment plan.

How many sessions of Rejuran and Vitaran are required?

Generally Approximately 3 procedures at intervals of 2 to 4 weeks We are providing guidance on how to do this.

With Rejuran and Vitaran, there are cases where you can feel changes in skin condition even after just a single treatment, but

Repeated treatments may be necessary to manage skin texture and fine lines step by step.

In the clinical trials for the approval of Vitaran A total of 4 times at 2-week intervals I performed the procedure.

In the early clinical trials of Rejuran A total of 3 times at 2-week intervals A method of performing the procedure was used.

In actual clinical practice, the number of sessions and intervals are usually determined by considering the following factors.

Skin thickness and degree of aging

The depth of fine lines

Treatment area

Pain and Embossing Recovery Speed

Reaction after previous procedure

The degree to which the skin has changed to the desired level

The number of procedures in a clinical trial is not an absolute standard required for everyone.

It is not necessarily better to receive more,

It is important to plan according to your skin condition and recovery response.

Reactions that may occur after Rejuran and Vitaran procedures

Because both products are injected directly into the skin

The following reactions may occur immediately after the procedure.

Embossing at the injection site

Redness and heat sensation

Swelling and tenderness

small bruise

itching or temporary discomfort

In most cases, it appears temporarily, but the speed of recovery varies from person to person.

If there is infection or inflammation at the procedure site, or if you are pregnant or breastfeeding,

If you are taking anticoagulants, antiplatelet agents, etc., you must inform the medical staff before the procedure.

Rejuran vs. Vitaran: When Should You Choose One?

lee Cases where Juran can be considered

If you prefer PN products with accumulated long usage experience

If you want to manage the skin texture and fine lines of your entire face together

If you want to choose from a variety of products depending on your purpose, such as for the eye area, face, or localized areas

Cases where Vitaran can be considered

If fine lines around the eyes are your main concern

If you are concerned about pain during the PN procedure

If you are sensitive to embossing after the procedure

If you prefer a pain-reducing formulation

However, the final product selection may vary depending on skin condition and the treatment area.

FAQ

Q1. Are Rejuran and Vitaran made of the same ingredient?

Both products use PN as the main ingredient.

However, due to differences in manufacturers, raw material purification processes, and product-specific viscosity and ionic environments,

It is not the exact same product.

Q2. Is Vitaran a generic version of Rejuran?

no.

Although it uses a common component called PN

These are products with separate manufacturers and medical device licenses.

Q3. Is Vitaran more effective than Rejuran?

Currently, based solely on direct comparison data, the wrinkle improvement effect of any single product

It is difficult to conclude that it is superior.

In the comparative study of Vitaran I and Rejuran I,

There was no significant difference in the degree of improvement in wrinkles at the corners of the eyes.

Q4. Is Vitaran less painful than Rejuran?

In the comparative study of Vitaran I and Rejuran I,

The average pain score of the children in Vita was lower.

However, the study scale is small, and there are individual differences in pain.

Q5. Which product lasts longer, Rejuran or Vitaran?

Sufficient research directly comparing the long-term effects of the two products under identical conditions is limited.

It is difficult to conclude which product lasts longer based solely on current data.

Q6. Does it also help with pores and skin texture?

There are cases where you may notice changes in skin texture and overall skin condition after a PN procedure.

However, if your main concerns are enlarged pores or acne scars, rather than PN Skin Booster alone

It is recommended to evaluate whether concurrent treatments such as laser or RF microneedling are necessary.

Rejuran vs. Vitaran Comparison Conclusion

Rejuran and Vitaran are both medical devices for tissue repair based on PN components.

Rejuran's strengths lie in its long history of use and diverse product line.

Vitaran is characterized by its approval for the improvement of fine lines at the corners of the eyes and research on Vitaran Child's pain reduction formulation.

While the core ingredients and expected direction of change of the two products are similar, there are differences in formulation and treatment experience.

However, rather than deciding based solely on the product name

Treatment area, skin thickness, degree of fine wrinkles, pain sensitivity

It is most important to evaluate and choose together.

Reference materials

Medical device manufacturing license for HP VITARAN I, etc., License No. 23-784.

Jeon W, et al. Efficacy of Ionization-Adjusted PN Filler in Minimizing Injection Pain: A Randomized, Patient-Blinded, Split-Face Study . Aesthetic Plastic Surgery. 2026.

Pak CS, et al. A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial… in the Correction of Crow's Feet . J Korean Med Sci. 2014.

PharmaResearch Rejuran · Rejuran HB plus official data.

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