[Doctor's Column] Juvereuk, Everything About Juvereuk Through Research Papers

Studying the outer and inner layers of the skin This is Director Kim Tae-hee of Sunae May Pure Clinic.

There is a name that is frequently mentioned in the skin booster market recently.

as soon as Jubelook no see.

When many people hear the word "skin booster," Like Rejuran, Vitaran, and water glow injections

I first think of “an injection that moisturizes the skin.”

However, Jubelock is in a slightly different position.

Juvelook is more than simple hydration

Collagen production and skin structure improvement Focused on

It can be understood as a collagen booster-type skin booster.

What is the key ingredient of Juvelook?

The ingredients of Juvelook are

PDLLA, Poly-D,L-lactic acid no see.

PDLLA is a biodegradable polymer material,

As it gradually breaks down inside the skin

Fibroblast Response and Collagen Remodeling inducing

It is known as a substance.

In recent PDLLA-related research PDLLA

Skin elasticity, wrinkles, tissue regeneration, scar remodeling It is summarized that it can be utilized in the back.

Why was HA included with Jubelook?

PDLLA + HA Hybrid The meaning of

PDLLA is a representative agent that induces long-term collagen remodeling. Biostimulatory substances However, PDLLA itself has limited effects in providing immediate hydration or improving the skin environment. the other side Hyaluronic Acid (HA) is the dermis of the skin Extracellular Matrix (ECM) As a key component, it plays a role in retaining moisture and creating a microenvironment where cell migration and wound healing occur. Therefore, the purpose of using PDLLA and HA together is to combine their different roles.

• HA → Improvement of initial moisture environment and ECM microenvironment

• PDLLA → Induces fibroblast activation and collagen remodeling over time

In other words, it can be understood as a hybrid concept where HA creates soil for regeneration and PDLLA induces long-term structural changes. In recent biostimulatory filler reviews as well, this hybrid approach Improvement of initial skin condition class Simultaneous long-term collagen regeneration It is explained as a design that takes this into consideration.

Why is collagen remodeling important?

Enlarged pores, fine lines, acne scars, loss of elasticity Is

On the surface, they appear to be different problems.

However, when viewed from the inside of the skin, they all have in common Related to the supporting structure of the dermis layer It works.

If the collagen and ECM structures of the dermis weaken

✔ Pores look saggy and

✔ Skin texture becomes rough and

✔ Fine wrinkles form and

✔ Acne scars look more prominent and

✔ Skin elasticity decreases.

Therefore, recent dermatological treatments have moved from simply making the surface smooth to

An approach that considers the dermal environment and collagen remodeling together It is changing into.

Which skin type is Jubelook Skin suitable for?

① Skin with enlarged pores

Enlarged pores are not simply a matter of sebum. If the elasticity of the dermis supporting the pores weakens, the pores may appear larger and more elongated. Juvelook can be utilized to improve the supporting structure around the pores through collagen remodeling.

② Skin with acne scars

Acne scars are closely related to structural defects in the dermis. PDLLA is also being studied in the fields of scar remodeling and tissue regeneration, and recent studies report that PDLLA can be utilized in the treatment of atrophic acne scars.

③ Skin with reduced elasticity

After the age of 30, the collagen and ECM structures within the skin gradually weaken. At this stage, simply supplying moisture is not enough

It is difficult to fully explain the decrease in skin density or elasticity. Juvelook can be considered as a collagen booster treatment aimed at improving skin elasticity and firmness.

④ Skin concerned about fine lines and texture

Juvelook is closer to a treatment that induces a regenerative response deep within the skin rather than a filler that creates immediate volume. Therefore, rather than for the purpose of immediately filling deep wrinkles...

It can be explained more naturally when aiming to improve fine lines, skin texture, and skin density.

When does Juveluck show effects?

Juvelook is not a treatment that fills volume immediately after injection like regular fillers, but rather Collagen remodeling proceeds over time It is a treatment that works. Therefore, rather than immediately after the procedure Over a few weeks to a few months Improvement of skin texture, elasticity, pores, and scars It is appropriate to describe it as a treatment that is expected to...

Jubelook, what to watch out for?

Because Juvelook belongs to the collagen stimulator class Procedure depth, concentration, dilution, injection volume, injection layer This is important. If injected too shallow or into an inappropriate layer Nodules, lumps, inflammatory reactions You must consider possibilities such as the above. In fact, after PDLLA-based procedures Foreign substance reaction Ina granuloma As there are reported cases, Juvelook is a procedure that requires a doctor's assessment of the skin condition and an accurate protocol, rather than being approached like a simple water-glow injection.

To summarize the Jubelook skin in one sentence

Juvelook Skin is not merely a treatment that supplies moisture to the skin, but rather A collagen skin booster that improves pores, scars, skin texture, and loss of elasticity by inducing collagen remodeling through PDLLA no see.

Not all skin boosters are the same. HA focuses on the hydration environment, PN on the recovery environment, and Juvelook on collagen remodeling.

So, Juvelook is better for those with thin and dry skin rather than Enlarged pores, scars, loss of elasticity, decreased skin density It is often a better fit for those who are also concerned.

📚 References

1. Lee K.W.A., et al. Poly-D,L-lactic Acid (PDLLA) Application in Dermatology. Polymers. 2024.

2. Seo S.B., et al. Skin rejuvenation effect of the combined PDLLA and non-cross-linked hyaluronic acid: A preliminary study. Journal of Cosmetic Dermatology. 2024.

3. Rho NK, et al. Needle-Free Jet Injection of Poly-(Lactic Acid) for Atrophic Acne Scars. Journal of Clinical Medicine. 2024.

4. Seo S.B., et al. Poly-D,L-lactic acid-enhanced atrophic scar treatment via transdermal microjet drug delivery. Skin Research and Technology. 2024.

5. Choi M, et al. Foreign-body granuloma formation in the lower eyelid after injection of poly-D,L-lactic acid as a collagen stimulator: a case report. Archives of Aesthetic Plastic Surgery. 2024.

[Mandatory Notices for Compliance with Medical Act]

※ All dermatological procedures may result in side effects, ranging from minor to major, such as erythema, swelling, burns, inflammation, and cheek hollowing, depending on an individual's skin condition and characteristics. This post is written for the purpose of providing medical information and does not guarantee 100% of the results of any specific procedure. Please be sure to have a thorough in-person consultation with experienced medical professionals before the procedure.

Director Kim Tae-hee of Maypure Clinic Sunae Branch

· Graduated from Chonnam National University School of Medicine

· Internal Medicine Specialist at Chonnam National University Hospital

· (Former) Clinical Professor, Department of Pulmonology, Gangnam Severance Hospital

· (Former) Assistant Professor, Department of Pulmonology, Kangnam Sacred Heart Hospital

· Regular member of the Korean Society of Internal Medicine

· Regular member of the Korean Society of Tuberculosis and Respiratory Diseases

· Member of the Korean Society of Cosmetology

👉 [Go to Maypure for free real-time consultation] https://pf.kakao.com/_ljPqE 

🔎 You can find more dermatology content by searching for "Sunae May Pure Blog" on Naver. Recommended Reading: "Skin Booster LAB Series"

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